Transgenic FacilityPublications
Long-term effects of mouse intracytoplasmic sperm injection with DNA-fragmented sperm on health and behavior of adult offspring.
Fernandez-Gonzalez, R., Moreira, P.N., Perez-Crespo, M., Sanchez-Martin, M., Ramirez, M.A., Pericuesta, E., Bilbao, A., Bermejo-Alvarez, P., de Dios Hourcade, J., de Fonseca, F.R. & Gutierrez-Adan, A.
Biol Reprod. 2008 Apr;78(4):761-72. Epub 2008 Jan 16.
PubMed
Improving the generation of genomic-type transgenic mice by ICSI.
Moreira, P.N., Pozueta, J., Perez-Crespo, M., Valdivieso, F., Gutierrez-Adan, A. & Montoliu, L.
Transgenic Res. 2007 Apr;16(2):163-8. Epub 2007 Feb 16.
PubMed
Effect of transgene concentration, flanking matrix attachment regions, and RecA-coating on the efficiency of mouse transgenesis mediated by intracytoplasmic sperm injection.
Moreira, P.N., Perez-Crespo, M., Ramirez, M.A., Pozueta, J., Montoliu, L. & Gutierrez-Adan, A.
Biol Reprod. 2007 Feb;76(2):336-43. Epub 2006 Oct 11.
PubMed
Differential effects of culture and nuclear transfer on relative transcript levels of genes with key roles during preimplantation.
Moreira, P.N., Fernandez-Gonzalez, R., Ramirez, M.A., Perez-Crespo, M., Rizos, D., Pintado, B. & Gutierrez-Adan, A.
Zygote. 2006 Feb;14(1):81-7.
PubMed
Epigenetic modifications in ES cell transposable elements and its possible association with the kinky tail phenotype in host chimeric mice.
Ramírez, M.A., Fernández-González, R., Pericuesta, E., Moreira, P.N., Pintado, B., Gutiérrez-Adán, A.
Trans Research (2006) - in press
Transcriptional and post-transcriptional regulation of retrotransposons IAP and MuERV-L affect pluripotency of mice ES cells.
Ramirez, M.A., Pericuesta, E., Fernandez-Gonzalez, R., Moreira, P., Pintado, B. & Gutierrez-Adan, A.
Reprod Biol Endocrinol. 2006 Nov 8;4:55.
PubMed
Generation of Yeast Artificial Chromosome Transgenic Mice by Intracytoplasmic Sperm Injection
Moreira, P.N., Pozueta, J., Giraldo, P., Gutiérrez-Adan, A., Montoliu, L.,
YAC protocols. Series Methods in Molecular Biology. Edited by Alasdair Mackenzie. Humana Press 2006, Totowa, New Jersey, 349 pp 151-161
Suboptimal in vitro culture conditions: An epigenetic origin of post-natal detrimental effects?
Moreira, P.N., Fernández-Gonzalez, R., Bilbao, A., Rodréguez De Fonseca, F., Gutiérrez-Adán, A.
Mol Reprod Dev (2006) - in press
Inadvertent transgenesis by conventional ICSI in mice.
Moreira, P.N., Fernandez-Gonzalez, R., Rizos, D., Ramirez, M., Perez-Crespo, M. & Gutierrez-Adan, A.
Hum Reprod. 2005 Dec;20(12):3313-7. Epub 2005 Aug 5.
PubMed
Human hepatocytes in mice receiving pre-immune injection with human cord blood cells.
Turrini, P., Monego, G., Gonzalez, J., Cicuzza, S., Bonanno, G., Zelano, G., Rosenthal, N., Paonessa, G., Laufer, R. & Padron, J.
Biochem Biophys Res Commun 2005 Jan 7;326(1):66-73.
PubMed
Species-related differences in blastocyst quality are associated with differences in relative mRNA transcription.
Rizos, D., Gutierrez-Adan, A., Moreira, P., O'Meara, C., Fair, T., Evans, A.C., Boland, M.P. & Lonergan, P.
Mol Reprod Dev. 2004 Dec;69(4):381-6.
PubMed
Efficient generation of transgenic mice with intact yeast artificial chromosomes by intracytoplasmic sperm injection.
Moreira, P.N., Giraldo, P., Cozar, P., Pozueta, J., Jimenez, A., Montoliu, L. & Gutierrez-Adan, A.
Biol Reprod. 2004 Dec;71(6):1943-7. Epub 2004 Jul 30.
PubMed
Effect of speed of development on mRNA expression pattern in early bovine embryos cultured in vivo or in vitro.
Gutierrez-Adan, A., Rizos, D., Fair, T., Moreira, P.N., Pintado, B., de la Fuente, J., Boland, M.P. & Lonergan, P.
Mol Reprod Dev. 2004 Aug;68(4):441-8.
PubMed
Long-term effect of in vitro culture of mouse embryos with serum on mRNA expression of imprinting genes, development, and behavior.
Fernandez-Gonzalez, R., Moreira, P., Bilbao, A., Jimenez, A., Perez-Crespo, M., Ramirez, M.A., Rodriguez De Fonseca, F., Pintado, B. & Gutierrez-Adan, A.
Proc Natl Acad Sci U S A. 2004 Apr 20;101(16):5880-5. Epub 2004 Apr 12.
PubMed
Animales Transgénicos. Los Retos medioambientales del Siglo XXI.
Pintado, B., Gutiérrez, Adán, A., Jiménez, A., Fernández, R., Moreira, P.N.
La Conservación de la Biodiversidad en Espana. Editor Montserrat Gomendio. Fundación BBVA 2004, Bilbao-Espana
Temporal divergence in the pattern of messenger RNA expression in bovine embryos cultured from the zygote to blastocyst stage in vitro or in vivo.
Lonergan, P., Rizos, D., Gutierrez-Adan, A., Moreira, P.M., Pintado, B., de la Fuente, J. & Boland, M.P.
Biol Reprod. 2003 Oct;69(4):1424-31. Epub 2003 Jun 25.
PubMed
Architectural defects in pronuclei of mouse nuclear transplant embryos.
Moreira, P.N., Robl, J.M. & Collas, P.
J Cell Sci. 2003 Sep 15;116(Pt 18):3713-20. Epub 2003 Jul 30.
PubMed
Mouse ICSI with frozen-thawed sperm: the impact of sperm freezing procedure and sperm donor strain.
Moreira, P.N., Jimenez, A., Fernandez, R., Bury-Madrid, N., De la Fuente, J., Pintado, B. & Gutierrez-Adan, A.
Mol Reprod Dev. 2003 Sep;66(1):98-103.
PubMed
Differential regulation of maternal and paternal chromosome condensation in mitotic zygotes.
Bomar, J., Moreira, P., Balise, J.J. & Collas, P.
J Cell Sci. 2002 Jul 15;115(Pt 14):2931-40.
PubMed
Effect of fibroblast donor cell age and cell cycle on development of bovine nuclear transfer embryos in vitro.
Kasinathan, P., Knott, J.G., Moreira, P.N., Burnside, A.S., Jerry, D.J. & Robl, J.M.
Biol Reprod. 2001 May;64(5):1487-93.
PubMed
p21(WAF1/Cip1) functions as a suppressor of malignant skin tumor formation and a determinant of keratinocyte stem-cell potential.
Topley, G.I., Okuyama, R., Gonzales, J.G., Conti, C. & Dotto, G.P.
Proc Natl Acad Sci U S A 1999 Aug 3;96(16):9089-94.
PubMed